How is obesity related to inflammation?

Obesity is linked to chronic low-grade inflammation due to the body's response to excess adipose tissue. When fat cells (adipocytes) increase in size and number, they can become dysfunctional. This dysfunction leads to the release of pro-inflammatory cytokines and other substances, which promote inflammation. Unlike acute inflammation, which is a short-term and localized response to injury or infection, chronic low-grade inflammation associated with obesity is systemic and persistent, contributing to various health issues, such as insulin resistance, type 2 diabetes, and cardiovascular diseases.

In this context, the presence of inflammation in obesity illustrates how metabolic processes can become dysregulated due to excess fat, signaling a pathway that has long-term health implications. Understanding this relationship is essential for developing strategies aimed at managing obesity and its associated health risks.